Fig. 8
From: FGFR3 signaling and function in triple negative breast cancer
Effect of PD173074 on proliferation and apoptosis in SUM185PE cells. a, Effect on cell cycle and apoptosis markers. SUM185PE cells were treated with PD173074 for 24 h, 48 h and 72 h and the effect on the indicated proteins analysed by Western blotting. UT indicates ‘untreated group’ as a control for DMSO addition, in order to monitor any effect of DMSO on cell cycle regulators. b, Effect of PD173074 on proliferation of SUM185PE and MDA-MB-468 cells. Cell proliferation was determined by direct cell counting. Error bars: mean ± standard error, of three biological replicates * indicates p-value of < 0.05, *** < 0.001