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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression

Fig. 6

DCX Nuclear import is promoted by GDNF. a Immunostaining of GDNF-treated GDCX and GDCXU251 stem cells compared with untreated GDCX cells. Scale bar, 20 μM. b Western blotting assay showing DCX nucleocytoplasmic expression in both MARK1-treated and untreated GDCX U251 cells. c Representative bioluminescence images comparing GDNF-treated GDCXC6 cells, GDNF-treated-wt C6, and untreated wt C6 cells at week 3 post-implantation. d Immunostaining of brain sections showing DCX nuclear accumulation intensity. Scale bars = 25 μm. Immunofluorescence image of invasive glioma markers, CD31 (E), and EGFR (F), Scale bars = 25 μm

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Cell Communication and Signaling

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