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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Dimerization of MORC2 through its C-terminal coiled-coil domain enhances chromatin dynamics and promotes DNA repair

Fig. 4

MORC2 can form a homodimer. a Schematic diagrams of the domain structure of human MORC2. CC, coiled-coil; CW-ZF, CW-type zinc finger. b-c HEK293T cells were transfected with Flag-MORC2, HA-MORC2 alone or in combination. After 48 h of transfection, total cellular lysates were subjected to IP analysis with an anti-Flag (b) or an anti-HA (c) antibody, followed by immunoblotting with the indicated antibodies. d HEK293T cells were transfected with HA-MORC2. After 48 h of transfection, total cellular lysates were subjected to cross-linking assay. e Purified MORC2 was visualized by coomasie brilliant blue staining. f Purified MORC2 was subjected to cross-linking assay and immunoblotting

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Cell Communication and Signaling

ISSN: 1478-811X