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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Dimerization of MORC2 through its C-terminal coiled-coil domain enhances chromatin dynamics and promotes DNA repair

Fig. 1

MORC2 attenuates histone and DNA interaction. a Knockout of MORC2 in HeLa and MCF-7 cells were carried out by the CRISPR/Cas9 system and validated by immunoblotting analysis with the indicated antibodies. b Nuclei were isolated from WT and MOCR2 KO HeLa or MCF-7 cells and subjected to salt solubilization assays. The core histones in salt soluble fractions were detected by immunoblotting using the indicated antibodies. NPM and hnRNPM are shown as loading controls

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Cell Communication and Signaling

ISSN: 1478-811X