RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans

Xu, Huihui; Fang, Tianshu; Omran, Raha Parvizi; Whiteway, Malcolm; Jiang, Linghuo

doi:10.1186/s12964-019-0473-9

Cell Communication and Signaling

Table 2 Functional category of 219 genes positively regulated by CaCrz1 in response to 0.2 M CaCl2

From: RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans

Systemic name	Standard name	Systemic name	Standard name	Systemic name	Standard name	Systemic name	Standard name	Systemic name	Standard name
Metabolism (13)
C1_04010C		C2_03640W	UGA11	C5_00220W	ROT2	C1_14060W		C1_11240C	CHO1
C2_01630W		C2_09150W	MIT1	CR_00620C	ARG1	C1_08330C	ADH2	C7_02500C	DPP3
C3_05810C	SKN1			C1_01620C
Cellular transport (23)
CR_03450W	HXT5	C5_04440C	SFC1	C3_03060W		C3_05270C	HGT5	C7_02910W	ENA21
C1_09220W		C2_09770C	INP51	C1_04630C				C7_00100W	FRP2
CR_05310W		C4_03110W		C3_07230W		C1_01100W	CCH1	C1_09400C	FTH1
C2_03800C		CR_09170C	SSU1	C2_06470W	RTA2	C2_07730W	YVC1	C1_06610C	HAK1
		CR_07100W	FLC2	CR_09680C	RTA4
Transcription (7)
CR_03890W	WOR3	C7_00970C	YOX1	C3_05780C	CRZ1	C1_05340C	ZCF2	C7_04230W	NRG1
CR_02300C		C4_04210C	SOH1
Signal transduction (3)
C5_02290W	PDE1	C4_06480C	CEK1	C7_00360W	DFI1
Protein fate (folding, modification, destination) (17)
C1_13220C	AKR1	C5_01440C		C2_00930C	VPS24	C5_01210W	VPS1	C4_03890W	PTP2
CR_00290W		C5_05060C		C4_04660C				C4_05810W
C6_03500C	SAP4	C2_01670C	STT3	C4_00070C		C7_03250C	PDI1	CR_00260W	KIN2
C1_08170C	BUL1	C2_08790W	JEM1
Cell rescue (9)
CR_06040W		CR_01730W	IFU5	C2_02060C	FMO1	C2_00680C	SOD5	C1_02700C
C2_09220W	DDR48	C3_00480C	DOT5	C2_05660W	PNG2	CR_05390W	PST3
Cell Cycle (6)
C1_09870W	HCM1	C6_03260W		C1_05170C	CUE5	C1_08570C	PCL2	C3_03850C	SOL1
C5_01680C	CCN1
Cell fate/development/cell type differentiation (14)
C4_03510C	HWP2	C7_00120W		C1_00850W	IHD2	C2_03040W	PLC2	C3_05190C	MCA1
C2_07930C	VRP1	C1_07770W	FGR6–3	C4_00600C	MUC1	C2_05260W	BUD14
C6_00940C		C2_00080C	FAV3	C4_01010C	DAG7	C1_01440C	POX18
Cell wall biosynthesis (34)
C5_02630C	MNN1	CR_00740C	BMT3	C3_01730C	UTR2	CR_04440C	RBR1	C3_02140C
C4_06540W	MNN4	C2_01560W	BMT5	CR_10480W	PGA1	C5_02460C	ECM331
C1_04900W	MNN15	C3_03450C	BMT7	C1_09080C	PGA6	CR_03790C	KRE1	C4_02720C
C2_01300C	MNN24	CR_00180C	CHT1	CR_08510W	PGA13	C6_01690W	ACF2
C2_03690C	MNN42	C2_02010C	CHT4	CR_02280W	PGA23	C5_04110W	SCW11	C2_05040C
C4_06990W	MNN46	CR_09020C	CHS2	CR_04900C	PGA39	C1_00220W	PHR2	C4_05100C	MYO5
C3_01830C	MNT2	C4_02900C	CRH11	C2_00100C	PGA52	C1_04000C	KTR4
Unknown (93)
CR_00380W		C3_07360W	DLD2	CR_10570C	YHB4	C3_04100W		C4_03590C	OSH3
C4_00410W		C3_07470W		C1_11970C		C2_09050C		C5_04330W
C2_08620W		C4_06470W		C1_12060C		C2_10150W		C5_04470C
C1_03870C		C5_03970W		C1_13240W		C2_10160W		C5_04480C
CR_07160C		C2_08960C		C1_13590W		C2_10720C		C5_04540C
C1_08610C		C1_00760W		C1_13810W		C3_02710W		C6_01250W
C3_01550C	TOS1	C1_01510W		C2_00110W		C3_04190W		C6_02210W
C5_04960W		C1_02370C		C2_00130W		C3_06670C		C6_04420W
C7_01700W		C1_04440W		C2_00750W		C3_06680C		C7_00310C
C1_03150C		C1_04470C		C2_00920W		C4_04190C		C7_00350C
C1_09800C	TVP18	C1_05450W		C2_00940W		C4_04200C		C7_01390W
		C1_05920W		C2_02220C		C4_05000W		C7_02370W
CR_00420W		C1_07990C		C2_02900W		C4_05250W		C7_03310W
		C1_08830C		C2_02910W		C4_05800C		CR_01020C
CR_08470W		C1_10060C		C2_03570C		C4_07260W		CR_02880W
C4_00860C		C1_10580C		C2_04750W		C5_00410W		CR_03780C
C3_02570W		C1_11260C		C2_05120C		C5_03430W		CR_06550C
C4_03870C		C1_11270W		C2_06630C		C5_04030W		CR_08990C
CR_05460W		C4_00980C	MRV1	C2_08910C

^#Underlined genes are shared CaCrz1-regulated genes that has been identified by DNA microarray in a previous study [28]. Shadowed genes are sequence homologues for 9 S. cerevisiae genes positively regulated by ScCrz1 in response to 0.2 M CaCl2 reported in a previous study [48].-

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