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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Targeting bone morphogenetic protein receptor 2 sensitizes lung cancer cells to TRAIL by increasing cytosolic Smac/DIABLO and the downregulation of X-linked inhibitor of apoptosis protein

Fig. 1

JL5 enhances cell death induced by TRAIL. H1299 cells (a-b) and A549 cells (c-d) were treated with JL5 and TRAIL alone and in combination for 24 h and the percent dead and number of live cells determined. Significantly more cell death occurred in H1299 cells treated with JL5 and TRAIL than either agent alone (c-d). In A549 cells, JL5 and TRAIL alone or in combination had little effect on cell death after 24 h. Data represents the mean percentage of dead cells and the number of live cells of 4 independent experiments

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