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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients

Fig. 5

High Grem1 levels correlates with high expression of stem cell markers in 66cl4. (a) Heat-map showing the RNA-Seq expression levels of 13 known stem cell markers (cut-off: expression level ≥ 1 in either cells or tumors of 67NR and 66cl4). Values are given in fragments per kilobase of transcripts per million fragments mapped (FPKM). (b) Representative histogram of 67NR and 66cl4 in vitro cultured cells stained with CD24 anti-mouse antibody. (c) Relationship between CD24 gene expression and RFS in breast cancer patients using KM plotter. (d) Relationship between combined CD24 and GREM1 expression and RFS in breast cancer patients using KM plotter

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