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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: S100P is a molecular determinant of E-cadherin function in gastric cancer

Fig. 1

S100P is associated with a gastric-specific signature. a Venn Diagram representing the number of genes defined as stomach-specific for each of the 4 datasets used. b The expression profile of 10 candidate genes was validated by qRT-PCR in commercial human RNAs representing a pool of at least three different tissue donors. c The S100P gene is over-expressed in GC cell lines of the diffuse type with dysfunctional E-cadherin (KATOIII and MKN45). Data represent mean value ±SD of at least three independent experiments normalized to the stomach. Statistical significance was evaluated with the Student’s t-test (*P ≤ 0.05)

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