Table 1 Different NFATC1 forms and mutants used in the experiments
NFATC1 proteins | Mutated sites | Length |
|---|---|---|
Wild type (WT) | none | full-length |
Dominant negative (DN) | none | 410–680 aa |
Constitutively active (mSRR) | all 11 serines mutated to alanines in the SRR (172–194) | 1–418 aa |
Double mutant (DM) | S245, S269 | full-length |
Triple mutant (TM) | S151, S153, T154, S256, S257, S335, T338, T339 | full-length |
Multi mutant (MM) | S151, S153, T154, S245, S256, S257, S269, S335, T338, T339 | full-length |