TY - JOUR AU - Yang, Nanyang AU - Liu, Sitong AU - Qin, Tian AU - Liu, Xintong AU - Watanabe, Nobumoto AU - Mayo, Kevin H. AU - Li, Jiang AU - Li, Xiaomeng PY - 2019 DA - 2019/11/21 TI - SUMO3 modification by PIAS1 modulates androgen receptor cellular distribution and stability JO - Cell Communication and Signaling SP - 153 VL - 17 IS - 1 AB - Abnormal reactivation of androgen receptor (AR) signaling in castration-resistant prostate cancer (CRPC) mainly results from overexpression and down-regulation of AR. Sumoylation of AR can influence its function. However, regulation of AR sumoylation by SUMO E3 ligases PIASs to modify AR distribution and stability are not well understood. SN - 1478-811X UR - https://doi.org/10.1186/s12964-019-0457-9 DO - 10.1186/s12964-019-0457-9 ID - Yang2019 ER -