TY - JOUR AU - Liu, Y. PY - 2011 DA - 2011// TI - Cellular and molecular mechanisms of renal fibrosis JO - Nat Rev Nephrol VL - 7 UR - https://doi.org/10.1038/nrneph.2011.149 DO - 10.1038/nrneph.2011.149 ID - Liu2011 ER - TY - JOUR AU - Zeisberg, M. AU - Neilson, E. G. PY - 2010 DA - 2010// TI - Mechanisms of tubulointerstitial fibrosis JO - J Am Soc Nephrol VL - 21 UR - https://doi.org/10.1681/ASN.2010080793 DO - 10.1681/ASN.2010080793 ID - Zeisberg2010 ER - TY - JOUR AU - Meran, S. AU - Steadman, R. PY - 2011 DA - 2011// TI - Fibroblasts and myofibroblasts in renal fibrosis JO - Int J Exp Pathol VL - 92 UR - https://doi.org/10.1111/j.1365-2613.2011.00764.x DO - 10.1111/j.1365-2613.2011.00764.x ID - Meran2011 ER - TY - JOUR AU - Sun, Y. B. AU - Qu, X. AU - Caruana, G. AU - Li, J. PY - 2016 DA - 2016// TI - The origin of renal fibroblasts/myofibroblasts and the signals that trigger fibrosis JO - Differentiation VL - 92 UR - https://doi.org/10.1016/j.diff.2016.05.008 DO - 10.1016/j.diff.2016.05.008 ID - Sun2016 ER - TY - JOUR AU - Lovisa, S. AU - LeBleu, V. S. AU - Tampe, B. AU - Sugimoto, H. AU - Vadnagara, K. AU - Carstens, J. L. PY - 2015 DA - 2015// TI - Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis JO - Nat Med VL - 21 UR - https://doi.org/10.1038/nm.3902 DO - 10.1038/nm.3902 ID - Lovisa2015 ER - TY - JOUR AU - LeBleu, V. S. AU - Taduri, G. AU - O'Connell, J. AU - Teng, Y. AU - Cooke, V. G. AU - Woda, C. PY - 2013 DA - 2013// TI - Origin and function of myofibroblasts in kidney fibrosis JO - Nat Med VL - 19 UR - https://doi.org/10.1038/nm.3218 DO - 10.1038/nm.3218 ID - LeBleu2013 ER - TY - JOUR AU - Grande, M. T. AU - Sanchez-Laorden, B. AU - Lopez-Blau, C. AU - Frutos, C. A. AU - Boutet, A. AU - Arevalo, M. PY - 2015 DA - 2015// TI - Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease JO - Nat Med VL - 21 UR - https://doi.org/10.1038/nm.3901 DO - 10.1038/nm.3901 ID - Grande2015 ER - TY - JOUR AU - Liu, Y. PY - 2010 DA - 2010// TI - New insights into epithelial-mesenchymal transition in kidney fibrosis JO - J Am Soc Nephrol VL - 21 UR - https://doi.org/10.1681/ASN.2008121226 DO - 10.1681/ASN.2008121226 ID - Liu2010 ER - TY - JOUR AU - Zeisberg, M. AU - Kalluri, R. PY - 2008 DA - 2008// TI - Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis JO - Front Biosci VL - 13 UR - https://doi.org/10.2741/3204 DO - 10.2741/3204 ID - Zeisberg2008 ER - TY - JOUR AU - Breton, J. D. AU - Heydet, D. AU - Starrs, L. M. AU - Veldre, T. AU - Ghildyal, R. PY - 2018 DA - 2018// TI - Molecular changes during TGFbeta-mediated lung fibroblast-myofibroblast differentiation: implication for glucocorticoid resistance JO - Physiol Rep VL - 6 UR - https://doi.org/10.14814/phy2.13669 DO - 10.14814/phy2.13669 ID - Breton2018 ER - TY - JOUR AU - Saika, S. AU - Ikeda, K. AU - Yamanaka, O. AU - Flanders, K. C. AU - Ohnishi, Y. AU - Nakajima, Y. PY - 2006 DA - 2006// TI - Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice JO - Am J Physiol Cell Physiol VL - 290 UR - https://doi.org/10.1152/ajpcell.00306.2005 DO - 10.1152/ajpcell.00306.2005 ID - Saika2006 ER - TY - JOUR AU - Zeisberg, M. AU - Hanai, J. AU - Sugimoto, H. AU - Mammoto, T. AU - Charytan, D. AU - Strutz, F. PY - 2003 DA - 2003// TI - BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury JO - Nat Med VL - 9 UR - https://doi.org/10.1038/nm888 DO - 10.1038/nm888 ID - Zeisberg2003 ER - TY - JOUR AU - Matsuno, Y. AU - Coelho, A. L. AU - Jarai, G. AU - Westwick, J. AU - Hogaboam, C. M. PY - 2012 DA - 2012// TI - Notch signaling mediates TGF-beta1-induced epithelial-mesenchymal transition through the induction of Snai1 JO - Int J Biochem Cell Biol VL - 44 UR - https://doi.org/10.1016/j.biocel.2012.01.021 DO - 10.1016/j.biocel.2012.01.021 ID - Matsuno2012 ER - TY - JOUR AU - Xiao, Z. AU - Zhang, J. AU - Peng, X. AU - Dong, Y. AU - Jia, L. AU - Li, H. PY - 2014 DA - 2014// TI - The Notch gamma-secretase inhibitor ameliorates kidney fibrosis via inhibition of TGF-beta/Smad2/3 signaling pathway activation JO - Int J Biochem Cell Biol VL - 55 UR - https://doi.org/10.1016/j.biocel.2014.08.009 DO - 10.1016/j.biocel.2014.08.009 ID - Xiao2014 ER - TY - JOUR AU - Munder, S. AU - Tischer, S. AU - Grundhuber, M. AU - Buchels, N. AU - Bruckmeier, N. AU - Eckert, S. PY - 2013 DA - 2013// TI - Notch-signalling is required for head regeneration and tentacle patterning in hydra JO - Dev Biol VL - 383 UR - https://doi.org/10.1016/j.ydbio.2013.08.022 DO - 10.1016/j.ydbio.2013.08.022 ID - Munder2013 ER - TY - JOUR AU - Whitsett, J. A. AU - Kalinichenko, V. V. PY - 2011 DA - 2011// TI - Notch and basal cells take center stage during airway epithelial regeneration JO - Cell Stem Cell VL - 8 UR - https://doi.org/10.1016/j.stem.2011.05.008 DO - 10.1016/j.stem.2011.05.008 ID - Whitsett2011 ER - TY - JOUR AU - Srinivasan, T. AU - Walters, J. AU - Bu, P. AU - Than, E. B. AU - Tung, K. L. AU - Chen, K. Y. PY - 2016 DA - 2016// TI - NOTCH signaling regulates asymmetric cell fate of fast- and slow-cycling Colon Cancer-initiating cells JO - Cancer Res VL - 76 UR - https://doi.org/10.1158/0008-5472.CAN-15-3198 DO - 10.1158/0008-5472.CAN-15-3198 ID - Srinivasan2016 ER - TY - JOUR AU - Sahlgren, C. AU - Gustafsson, M. V. AU - Jin, S. AU - Poellinger, L. AU - Lendahl, U. PY - 2008 DA - 2008// TI - Notch signaling mediates hypoxia-induced tumor cell migration and invasion JO - Proc Natl Acad Sci U S A VL - 105 UR - https://doi.org/10.1073/pnas.0802047105 DO - 10.1073/pnas.0802047105 ID - Sahlgren2008 ER - TY - JOUR AU - Bielesz, B. AU - Sirin, Y. AU - Si, H. AU - Niranjan, T. AU - Gruenwald, A. AU - Ahn, S. PY - 2010 DA - 2010// TI - Epithelial notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans JO - J Clin Invest VL - 120 UR - https://doi.org/10.1172/JCI43025 DO - 10.1172/JCI43025 ID - Bielesz2010 ER - TY - JOUR AU - Kopan, R. AU - Ilagan, M. X. PY - 2009 DA - 2009// TI - The canonical notch signaling pathway: unfolding the activation mechanism JO - Cell VL - 137 UR - https://doi.org/10.1016/j.cell.2009.03.045 DO - 10.1016/j.cell.2009.03.045 ID - Kopan2009 ER - TY - JOUR AU - Guo, D. AU - Ye, J. AU - Dai, J. AU - Li, L. AU - Chen, F. AU - Ma, D. PY - 2009 DA - 2009// TI - Notch-1 regulates Akt signaling pathway and the expression of cell cycle regulatory proteins cyclin D1, CDK2 and p21 in T-ALL cell lines JO - Leuk Res VL - 33 UR - https://doi.org/10.1016/j.leukres.2008.10.026 DO - 10.1016/j.leukres.2008.10.026 ID - Guo2009 ER - TY - JOUR AU - Murea, M. AU - Park, J. K. AU - Sharma, S. AU - Kato, H. AU - Gruenwald, A. AU - Niranjan, T. PY - 2010 DA - 2010// TI - Expression of notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function JO - Kidney Int VL - 78 UR - https://doi.org/10.1038/ki.2010.172 DO - 10.1038/ki.2010.172 ID - Murea2010 ER - TY - JOUR AU - Sharma, S. AU - Sirin, Y. AU - Susztak, K. PY - 2010 DA - 2010// TI - The story of notch and chronic kidney disease JO - Curr Opin Nephrol Hypertens VL - 20 UR - https://doi.org/10.1097/MNH.0b013e3283414c88 DO - 10.1097/MNH.0b013e3283414c88 ID - Sharma2010 ER - TY - JOUR AU - Bai, Y. AU - Lu, H. AU - Lin, C. AU - Xu, Y. AU - Hu, D. AU - Liang, Y. PY - 2016 DA - 2016// TI - Sonic hedgehog-mediated epithelial-mesenchymal transition in renal tubulointerstitial fibrosis JO - Int J Mol Med VL - 37 UR - https://doi.org/10.3892/ijmm.2016.2546 DO - 10.3892/ijmm.2016.2546 ID - Bai2016 ER - TY - JOUR AU - Bai, Y. AU - Lu, H. AU - Wu, C. AU - Liang, Y. AU - Wang, S. AU - Lin, C. PY - 2014 DA - 2014// TI - Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway JO - Biochem Pharmacol VL - 92 UR - https://doi.org/10.1016/j.bcp.2014.09.002 DO - 10.1016/j.bcp.2014.09.002 ID - Bai2014 ER - TY - JOUR AU - Dovey, H. F. AU - John, V. AU - Anderson, J. P. AU - Chen, L. Z. AU - Saint, A. P. AU - Fang, L. Y. PY - 2001 DA - 2001// TI - Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain JO - J Neurochem VL - 76 UR - https://doi.org/10.1046/j.1471-4159.2001.00012.x DO - 10.1046/j.1471-4159.2001.00012.x ID - Dovey2001 ER - TY - JOUR AU - Pozdzik, A. A. AU - Salmon, I. J. AU - Debelle, F. D. AU - Decaestecker, C. AU - Branden, C. AU - Verbeelen, D. PY - 2008 DA - 2008// TI - Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation JO - Kidney Int VL - 73 UR - https://doi.org/10.1038/sj.ki.5002714 DO - 10.1038/sj.ki.5002714 ID - Pozdzik2008 ER - TY - JOUR AU - Bai, Y. AU - Lu, H. AU - Hu, L. AU - Hong, D. AU - Ding, L. AU - Chen, B. PY - 2014 DA - 2014// TI - Effect of Sedum sarmentosum BUNGE extract on aristolochic acid-induced renal tubular epithelial cell injury JO - J Pharmacol Sci VL - 124 UR - https://doi.org/10.1254/jphs.13216FP DO - 10.1254/jphs.13216FP ID - Bai2014 ER - TY - JOUR AU - Li, Y. AU - Liu, Z. AU - Guo, X. AU - Shu, J. AU - Chen, Z. AU - Li, L. PY - 2006 DA - 2006// TI - Aristolochic acid I-induced DNA damage and cell cycle arrest in renal tubular epithelial cells in vitro JO - Arch Toxicol VL - 80 UR - https://doi.org/10.1007/s00204-006-0090-4 DO - 10.1007/s00204-006-0090-4 ID - Li2006 ER - TY - JOUR AU - Leask, A. AU - Abraham, D. J. PY - 2004 DA - 2004// TI - TGF-beta signaling and the fibrotic response JO - FASEB J VL - 18 UR - https://doi.org/10.1096/fj.03-1273rev DO - 10.1096/fj.03-1273rev ID - Leask2004 ER - TY - JOUR AU - Lai, E. C. PY - 2004 DA - 2004// TI - Notch signaling: control of cell communication and cell fate JO - Development VL - 131 UR - https://doi.org/10.1242/dev.01074 DO - 10.1242/dev.01074 ID - Lai2004 ER - TY - JOUR AU - Sirin, Y. AU - Susztak, K. PY - 2011 DA - 2011// TI - Notch in the kidney: development and disease JO - J Pathol VL - 226 UR - https://doi.org/10.1002/path.2967 DO - 10.1002/path.2967 ID - Sirin2011 ER - TY - JOUR AU - Barak, H. AU - Surendran, K. AU - Boyle, S. C. PY - 2012 DA - 2012// TI - The role of Notch signaling in kidney development and disease JO - Adv Exp Med Biol VL - 727 UR - https://doi.org/10.1007/978-1-4614-0899-4_8 DO - 10.1007/978-1-4614-0899-4_8 ID - Barak2012 ER - TY - JOUR AU - Penton, A. L. AU - Leonard, L. D. AU - Spinner, N. B. PY - 2012 DA - 2012// TI - Notch signaling in human development and disease JO - Semin Cell Dev Biol VL - 23 UR - https://doi.org/10.1016/j.semcdb.2012.01.010 DO - 10.1016/j.semcdb.2012.01.010 ID - Penton2012 ER - TY - JOUR AU - Edeling, M. AU - Ragi, G. AU - Huang, S. AU - Pavenstadt, H. AU - Susztak, K. PY - 2016 DA - 2016// TI - Developmental signalling pathways in renal fibrosis: the roles of notch, Wnt and Hedgehog JO - Nat Rev Nephrol VL - 12 UR - https://doi.org/10.1038/nrneph.2016.54 DO - 10.1038/nrneph.2016.54 ID - Edeling2016 ER - TY - JOUR AU - Choi, A. AU - Nam, S. A. AU - Kim, W. Y. AU - Park, S. H. AU - Kim, H. AU - Yang, C. W. PY - 2017 DA - 2017// TI - Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice JO - Korean J Intern Med VL - 33 UR - https://doi.org/10.3904/kjim.2016.230 DO - 10.3904/kjim.2016.230 ID - Choi2017 ER - TY - JOUR AU - Sassoli, C. AU - Chellini, F. AU - Pini, A. AU - Tani, A. AU - Nistri, S. AU - Nosi, D. PY - 2013 DA - 2013// TI - Relaxin prevents cardiac fibroblast-myofibroblast transition via notch-1-mediated inhibition of TGF-beta/Smad3 signaling JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0063896 DO - 10.1371/journal.pone.0063896 ID - Sassoli2013 ER - TY - JOUR AU - Dees, C. AU - Tomcik, M. AU - Zerr, P. AU - Akhmetshina, A. AU - Horn, A. AU - Palumbo, K. PY - 2011 DA - 2011// TI - Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis JO - Ann Rheum Dis VL - 70 UR - https://doi.org/10.1136/ard.2010.134742 DO - 10.1136/ard.2010.134742 ID - Dees2011 ER - TY - JOUR AU - Lamouille, S. AU - Xu, J. AU - Derynck, R. PY - 2014 DA - 2014// TI - Molecular mechanisms of epithelial-mesenchymal transition JO - Nat Rev Mol Cell Biol VL - 15 UR - https://doi.org/10.1038/nrm3758 DO - 10.1038/nrm3758 ID - Lamouille2014 ER - TY - JOUR AU - Masaki, S. AU - Masutani, H. AU - Yoshihara, E. AU - Yodoi, J. PY - 2012 DA - 2012// TI - Deficiency of thioredoxin binding protein-2 (TBP-2) enhances TGF-beta signaling and promotes epithelial to mesenchymal transition JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0039900 DO - 10.1371/journal.pone.0039900 ID - Masaki2012 ER - TY - JOUR AU - Hinz, B. AU - Phan, S. H. AU - Thannickal, V. J. AU - Galli, A. AU - Bochaton-Piallat, M. L. AU - Gabbiani, G. PY - 2007 DA - 2007// TI - The myofibroblast: one function, multiple origins JO - Am J Pathol VL - 170 UR - https://doi.org/10.2353/ajpath.2007.070112 DO - 10.2353/ajpath.2007.070112 ID - Hinz2007 ER - TY - JOUR AU - Tomasek, J. J. AU - Gabbiani, G. AU - Hinz, B. AU - Chaponnier, C. AU - Brown, R. A. PY - 2002 DA - 2002// TI - Myofibroblasts and mechano-regulation of connective tissue remodelling JO - Nat Rev Mol Cell Biol VL - 3 UR - https://doi.org/10.1038/nrm809 DO - 10.1038/nrm809 ID - Tomasek2002 ER - TY - JOUR AU - Zavadil, J. AU - Cermak, L. AU - Soto-Nieves, N. AU - Bottinger, E. P. PY - 2004 DA - 2004// TI - Integration of TGF-beta/Smad and Jagged1/notch signalling in epithelial-to-mesenchymal transition JO - EMBO J VL - 23 UR - https://doi.org/10.1038/sj.emboj.7600069 DO - 10.1038/sj.emboj.7600069 ID - Zavadil2004 ER - TY - JOUR AU - Morrissey, J. AU - Guo, G. AU - Moridaira, K. AU - Fitzgerald, M. AU - McCracken, R. AU - Tolley, T. PY - 2002 DA - 2002// TI - Transforming growth factor-beta induces renal epithelial jagged-1 expression in fibrotic disease JO - J Am Soc Nephrol VL - 13 UR - https://doi.org/10.1097/01.ASN.0000017905.77985.4A DO - 10.1097/01.ASN.0000017905.77985.4A ID - Morrissey2002 ER - TY - JOUR AU - Zhao, Y. AU - Qiao, X. AU - Tan, T. K. AU - Zhao, H. AU - Zhang, Y. AU - Liu, L. PY - 2016 DA - 2016// TI - Matrix metalloproteinase 9-dependent notch signaling contributes to kidney fibrosis through peritubular endothelial-mesenchymal transition JO - Nephrol Dial Transplant VL - 32 ID - Zhao2016 ER - TY - JOUR AU - Lanz, T. A. AU - Himes, C. S. AU - Pallante, G. AU - Adams, L. AU - Yamazaki, S. AU - Amore, B. PY - 2003 DA - 2003// TI - The gamma-secretase inhibitor N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester reduces a beta levels in vivo in plasma and cerebrospinal fluid in young (plaque-free) and aged (plaque-bearing) Tg2576 mice JO - J Pharmacol Exp Ther VL - 305 UR - https://doi.org/10.1124/jpet.102.048280 DO - 10.1124/jpet.102.048280 ID - Lanz2003 ER - TY - JOUR AU - Zheng, Y. H. AU - Li, F. D. AU - Tian, C. AU - Ren, H. L. AU - Du, J. AU - Li, H. H. PY - 2013 DA - 2013// TI - Notch gamma-secretase inhibitor dibenzazepine attenuates angiotensin II-induced abdominal aortic aneurysm in ApoE knockout mice by multiple mechanisms JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0083310 DO - 10.1371/journal.pone.0083310 ID - Zheng2013 ER - TY - JOUR AU - Groth, C. AU - Alvord, W. G. AU - Quinones, O. A. AU - Fortini, M. E. PY - 2010 DA - 2010// TI - Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of notch and APP JO - Mol Pharmacol VL - 77 UR - https://doi.org/10.1124/mol.109.062471 DO - 10.1124/mol.109.062471 ID - Groth2010 ER - TY - JOUR AU - Chen, Y. AU - Zheng, S. AU - Qi, D. AU - Guo, J. AU - Zhang, S. AU - Weng, Z. PY - 2012 DA - 2012// TI - Inhibition of notch signaling by a gamma-secretase inhibitor attenuates hepatic fibrosis in rats JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0046512 DO - 10.1371/journal.pone.0046512 ID - Chen2012 ER - TY - JOUR AU - Zhang, X. AU - Du, G. AU - Xu, Y. AU - Li, X. AU - Fan, W. AU - Chen, J. PY - 2015 DA - 2015// TI - Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes JO - Lab Investig VL - 96 UR - https://doi.org/10.1038/labinvest.2015.149 DO - 10.1038/labinvest.2015.149 ID - Zhang2015 ER -