Table 2 Transcriptomic data of glycolysis and lipogenesis pathways in 4NQO induced mouse tongue cancer group and in BME fed group
Genes | Cancer compared to normal (Fold) | BME compared to cancer (Fold) |
|---|---|---|
Glucose transporter-1 (Glut1/SLC2A1) | 8.13 | −2.9*** |
Hexokinase-1 (HK1) | 1.3 | −1.35* |
Hexokinase-2 (HK2) | 1.4 | 1.07 |
Phosphofructo kinase (platelet) (PFKP) | 1.8*** | −1.4 |
Phosphogluco isomerase (GPI) | −1.04 | 1.06 |
Triosphosphate isomerase (TPI) | −1.1 | −1.1 |
Enolase- 1 (ENO-1) | 3.08*** | −1.8* |
Pyruvate kinase muscle (PKM) | 1.2 | −1.3 |
Pyruvate dehydrogenase kinase 3 (PDK3) | 1.7** | −1.1 |
Lactate dehydrogenase alpha (LDHA) | 1.9* | −1.5 |
ATP Citrate Lyase (ACLY) | 1.2 | −1.3* |
Acetyl-CoA Carboxylase 1 (ACC1) | 1.02 | −1.33 |
Fatty Acid Synthase (FASN) | 1.11 | −1.5* |