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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Linoleic acid improves assembly of the CII subunit and CIII2/CIV complex of the mitochondrial oxidative phosphorylation system in heart failure

Fig. 4

Amount of supercomplexes and complex II significantly correlated with cardiolipin content in mitochondria isolated from siCRLS1-treated cardiomyocytes. Assays were started at 96 h after the transfection with 25 or 50 nmol siRNA (n = 3 each). a. The cardiolipin content in mitochondria isolated from siCRLS1 cardiomyocytes are shown relative to Irr (n = 6). b. Correlation between cardiolipin content and the amount of respirasomes (I/III2/IVn). c. Correlation between cardiolipin content and the amount of complex III2/IV. d. Correlation between cardiolipin content and the amount of complex II. Pearson correlation coefficients (R) and p-values are shown

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