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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Identification of Cancer–associated metabolic vulnerabilities by modeling multi-objective optimality in metabolism

Fig. 1

Four-objective optimization model for cancer metabolism. (a) Illustration of the four metabolic objectives incorporated in this model and mathematical description of its components. (b) The sampled Pareto surface projected on four ternary combinations of included objectives. Data points are presented in shade to depict the shape of Pareto surface. (c) Distributions of values for binary combinations of objectives in the sampled Pareto solutions

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