Skip to main content
Fig. 7 | Cell Communication and Signaling

Fig. 7

From: CXCL1-LCN2 paracrine axis promotes progression of prostate cancer via the Src activation and epithelial-mesenchymal transition

Fig. 7

Schematic diagram of CXCL1-LCN2 paracrine axis in prostate cancer microenvironment. CXCL1 secreted from myofibroblast directly enhances prostate cancer cell migration (â‘ ); CXCL1 recruits neutrophils to prostate cancerous lesion (â‘¡); LCN secreted from neutrophil further promotes tumor cells migration (â‘¢); Activation of Src family kinases contributes to highly aggressive phenotype of prostate cancer cells stimulated by CXCL1 and LCN2 (â‘£)

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X