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Table 2 Correlation of 4.1B expression with clinical parameters in GC patients

From: 4.1B suppresses cancer cell proliferation by binding to EGFR P13 region of intracellular juxtamembrane segment

Variables

No.(n = 102)

4.1Bexpression

χ2

p value

Negative(46)

Positive(56)

Age (years)

 <65

49

21

28

0.191

0.662

 ≥ 65

53

25

28

  

Gender

 Male

59

27

32

0.025

0.847

 Female

43

19

24

  

Helicobacter pylori infection

 Positive

56

24

32

0.252

0.616

 Negative

46

22

24

  

Tumor size

 <5 cm

56

19

37

6.257

0.012*

 ≥ 5 cm

46

27

19

  

Tumor location

 Cardia

26

6

20

6.956

0.073

 body

26

13

13

  

 Antrum

41

22

19

  

 Whole

9

5

4

  

WHO classification

 Tubular

32

10

22

5.281

0.152

 Signet-ring cell

29

14

15

  

 Mucinous

37

21

16

  

 Others

4

1

3

  

Pathologic differentiation

 G1

14

4

10

8.025

0.018*

 G2

35

11

24

  

 G3

53

31

22

  

Vascular invasion

 Negative

42

15

27

2.539

0.111

 Positive

60

31

29

  

Neural invasion

 Negative

43

17

26

0.929

0.335

 Positive

59

29

30

  

Depth of invasion

 T1 + T2

26

8

18

2.894

0.089

 T3 + T4

76

38

38

  

Lymph metastasis

 N0

26

7

19

4.656

0.031*

 N1 + N2 + N3

76

39

37

  

TNM stage

 I

19

3

16

8.589

0.014*

 II

26

12

14

  

 III

57

31

26

  
  1. * p < 0.05