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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: 4.1B suppresses cancer cell proliferation by binding to EGFR P13 region of intracellular juxtamembrane segment

Fig. 2

Effects of 4.1B on the proliferation of transfected GC cell lines in vitro. a 4.1B expression in MGC-803 and MKN-45 GC cell lines (a) and their proliferation ability (b). b mRNA level and localization of 4.1B was examined by Real-time PCR (a) and confocal microscopy (b) in 4.1B-overexpressing MGC-803. Scale bars, 20 μm. 4.1B expression in 4.1B-overexpressing MGC-803 cell lines (c) and their proliferation ability change (d). c 4.1B expression in 4.1B KO MKN-45 GC cell lines (a) and their proliferation ability change (b). * p < 0.05, ** p < 0.01, *** p < 0.001

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