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Table 1 Clinicopathologic characteristics of breast cancer patients with different ITM2A expression from the TCGA database

From: Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction

Characteristic

No. (%) of patients

Correlation

Total

ITM2A high

ITM2A low

Chi-square

p value

Age in years

1208

  

6.048

0.0139

  ≤ 60

 

285

362

  

  > 60

 

208

353

  

ER status

1145

  

3.016

0.0824

 Positive

 

382

504

  

 Negative

 

96

163

  

PR status

1142

  

6.734

0.0095

 Positive

 

340

427

  

 Negative

 

136

239

  

HER2 level

   

2.726

0.2559

 1+

 

122

160

  

 2+

 

75

134

  

 3+

 

39

57

  

T classification

1205

  

12.67

0.0018

 T1

 

145

164

  

 T2

 

256

443

  

 T3/T4

 

92

105

  

N classification

1185

  

8.345

0.0394

 N0

 

261

300

  

 N1

 

220

191

  

 N2

 

68

64

  

 N3

 

49

32

  

Stage

1199

  

14.62

0.0022

 I

 

92

110

  

 II

 

254

432

  

 III

 

134

141

  

 Other

 

11

25

  
  1. ER estrogen receptor, PR progesterone receptor, HER2 receptor tyrosine-protein kinase erbB-2