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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Inhibition of T cell immunoglobulin and mucin-1 (TIM-1) protects against cerebral ischemia-reperfusion injury

Fig. 2

TIM-1 blocking antibody effectively protects against brain tissue damage in a model of MCAO. a-b The infarct size was measured in the Black, MCAO, and TIM-1 Ab + MCAO groups by TTC staining. c Bederson scores of the mice after MCAO following treatment with or without TIM-1 Ab. d-e Cellular apoptosis was examined using TdT-mediated biotin-16-dUTP nick-end labeling (TUNEL) assay (magnification: 400×; *P < 0.05; **P < 0.01; ***p < 0.001 vs Black. f Western blot detecting the level of apoptosis-related protein expression (Bax, Bcl-2, and Bcl-xl)

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Cell Communication and Signaling

ISSN: 1478-811X