Fig. 9From: ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cellsThe representation illustrates a proposed model for ITCH-dependent proteasomal degradation of c-FLIP induced by 9F7-F11 to promote DR5/caspase-8 apoptosis. See text for detailsBack to article page