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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Wnt signaling: a promising target for osteoarthritis therapy

Fig. 3

Proposed model of the role of canonical and noncanonical wnt signaling pathway mediated network that regulating chondrocyte function, the activiation of Wnt signaling and their interaction between either canonical and noncanonical, or Hedgehog, MAPK, NF/κB, BMP/TGF-β/Smad and Notch signaling pathways, are assiciated with chondrocyte differentiation, hypertrophy, catabolism, anabolism and thereby involed in OA development, and marked with event-specific colored line or arrows

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