Fig. 6From: Reversal effect of FW-04-806, a macrolide dilactone compound, on multidrug resistance mediated by ABCB1 and ABCG2 in vitro and in vivoEffect of FW-04-806 on the expression of ABCB1, ABCG2. The protein level of ABCB1 (a) and ABCG2 (c) were detected by Western blot assay. Real-time quantitative PCR assay was performed to quantify the mRNA levels of ABCB1 in KBv200 (b) and ABCG2 in H460/MX20 cells (d). A representative result from three independent experiments was shown in each panel. Data represent mean ± SD from three independent experimentsBack to article page