Skip to main content
Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Reversal effect of FW-04-806, a macrolide dilactone compound, on multidrug resistance mediated by ABCB1 and ABCG2 in vitro and in vivo

Fig. 1

The structure of FW-04-806 and its cytotoxicity in drug resistant cell lines and their parental cell lines. The structure of FW-04-806 (a). Cytotoxicity of FW-04-806 on KBv200 and KB cells (b), S1-MI-80 and S1cells (c), K562/adr and K562 cells (d), H460/MX20 and H460 cells (e), MCF-7/adr and MCF-7 cells (f), HEK293/pcDNA3.1 and stable ABCG2 transfected HEK293/ABCG2-R2 cells (g) and HEK293/pcDNA3.1 and stable ABCB1 transfected HEK293/ABCB1 cells (h). All cells were treated with different concentrations of FW-04-806 for 72 h. Data are expressed as mean ± SD from three independent experiments

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X