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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213

Fig. 2

CAPE treatment suppressed protein level of AR and PSA but not mRNA of AR. Protein expression level of AR, phospho-AR Ser308 in LNCaP 104-S cells (a) and 104-R1 (b) cells as well as PSA in in LNCaP 104-S cells (c) and LNCaP 104-R1 cells (d) treated with DHT and CAPE for 48 h was determined by Western blotting. The β-actin was used as loading control. The mRNA expression level of AR in LNCaP 104-S cells (e) and LNCaP 104-R1 cells (f) treated with indicated concentration of DHT and CAPE for 48 h was analyzed by qRT-PCR. GAPDH was used as loading control

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