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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice

Fig. 3

Podocyte-specific loss of PP2A results in progressive glomerulosclerosis and interstitial fibrosis. a Representative HE images of glomeruli from Pod-PP2A-KO mice revealing histological evidence of dilated glomerular capillary loops at 5 weeks of age (arrowheads), which progresses to diffuse glomerulosclerosis by 8 weeks. Scale bar: 50 μm. b Proteinaceous casts (arrowhead) and severe interstitial fibrosis are observed in kidney section from Pod-PP2A-KO mice at 8 weeks of age by the HE, Masson, and PAS staining. Scale bar: 50 μm

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