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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: A novel population of extracellular vesicles smaller than exosomes promotes cell proliferation

Fig. 2

Inhibitiors of exosome production inhibit secretion of P100 vesicles but not P200 vesicles. a, b The histograms show (a) the numbers of particles in the P100 fractions and (b) those in the P200 fractions after treatment with BFA (red) and control (blue). c The bar graphs show the number of vesicles in the P100 and P200 fractions isolated from HEK293 cell CM after BFA treatment (shaded) and control (solid). d, e The histograms show (d) particles in the P100 fractions and (e) particles in the P200 fractions after treatment with GW4869 (red) and control (blue). f The bar graphs show the number of vesicles in the P100 and P200 fractions from GW4869 treated HEK293 CM (shaded) and control (solid). Values = mean ± S.D. *Significant difference analyzed by t-test (*p < 0.05,**p < 0.01,***p < 0.001)

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