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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Inhibition of cyclin E1 sensitizes hepatocellular carcinoma cells to regorafenib by mcl-1 suppression

Fig. 1

High expression of CCNE1 is related to poor hepatocellular carcinoma outcomes. a mRNA expression of CCNA1, CCND1, and CCNE1 in the TCGA liver cancer database. b Overall survival (OS) rates of HCC patients with various levels of CCNA1, CCND1, and CCNE1 expression. c Expression levels of CCNA1, CCND1, and CCNE1 in the indicated HCC cell lines. d The cell viability of the indicated HCC cells treated with various concentrations of sorafenib. e The cell viability of the indicated HCC cells treated with various concentrations of regorafenib. The western blots were repeated for 3 times, and representative data were shown. N = 3 for D and E. N, P > 0.05, **, P < 0.05s

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