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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: Histone deacetylase 1 induced by neddylation inhibition contributes to drug resistance in acute myelogenous leukemia

Fig. 8

Tumor growth of HL-60 xenograft in mice. a Tumor volume of the HL-60 xenograft overexpressing HDAC1 in mice treated with doxorubicin or Panobinostat. b Representative tumor morphology. Panob, Panobinostat. DOX, doxorubicin. Data are the mean ± SD of six xenografts of mice. *P < 0.05, **P < 0.01 vs. LV control + doxorubicin, ##P < 0.01 vs. LV-HDAC1 + doxorubicin

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