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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling pathways

Fig. 1

SAE1 upregulation in human glioma tissues correlates with the patient’s survival. a SAE1 mRNA expression was measured by qRT-PCR between 3 random chosen HGTs and their paired PBTs. The relative transcript levels were normalized to GAPDH. *p < 0.05, **p < 0.01. b SAE1 protein levels were shown by Western blot in 3 pairs of HGTs and PBTs. HGTs: human glioma tissues; PBTs: para-cancerous brain tissues. c Immunohistochemical staining of SAE1 in PBTs and giloma tissues with different pathologic grades (400×). d The hematoxylin-eosin (H&E) staining of glioma tissue (400×). e Kaplan-Meier overall survival curves for glioma patients based on SAE1 levels. Glioma patients with high expression of SAE1 had a worse postoperative overall survival

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