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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Pre-clinical blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces regression of activated B-cell lymphoma

Fig. 3

a Mean and standard deviation of flow cytometry percentages of activated CD4 and CD8 T-cells expressing CD62L and CD44 activation markers in LMP1/CD40-expressing mice after injection of isotype control (Ctrl) or anti-PD-L1 (αPD-L1) antibody. b Flow cytometry Mean Fluorescence Intensity (MFI) of PD-1 on CD4 and CD8 T-cells in Ctrl and αPD-L1 treated LMP1/CD40-expressing mice. Statistical significance was determined by unpaired t-test (**P < 0.01; *P < 0.05)

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