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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Elevated Kallikrein-binding protein in diabetes impairs wound healing through inducing macrophage M1 polarization

Fig. 3

KBP increases monocyte counts in the blood and macrophage accumulation in wounds. a, b Representative immunohistochemical results and greyscale analysis of F4/80 (a macrophage marker) in the wounds of WT/KBP-TG mice at D10. c, d Representative immunohistochemical results and greyscale analysis of F4/80 in the wounds of diabetic mice treated with IgG/KBP antibody at D10. e The mRNA expression of F4/80 in the wounds of WT/KBP-TG mice at different time points. f The mRNA expression of F4/80 in the wounds of diabetic mice treated with IgG/KBP antibody at different time points. g Representative FACS results and the quantification of CD115+ monocytes in the peripheral blood of WT/KBP-TG mice. Data are presented as the mean ± SD. n = 3; * p < 0.05

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