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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Interleukin-32θ inhibits tumor-promoting effects of macrophage-secreted CCL18 in breast cancer

Fig. 1

Opposing expression patterns between IL-32θ and CCL18 in selected tumor tissues. The mRNA expression levels of IL-32θ in tumor tissues were determined by RT-PCR, and then quantitated using ImageJ software. mRNA expression levels of CCL-18, IL-1β, TNF-α, and CCL5 were quantitated by real-time PCR. a mRNA expression of IL-32θ in CD206 positive (n = 33) and negative (n = 57) tumor tissue groups. b mRNA expression in IL-32 positive (n = 35) and negative (n = 55) tumor tissue groups. c Protein secretion level of CCL18, IL-1β, TNF-α, and CCL5 in IL-32 positive (n = 17) and negative (n = 38) tumor tissue groups. Plot are box and whisker plots. A line drawn across the box represents the median. Statistics were analyzed using Mann-Whitney U test: *, p < 0.05

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