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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways

Fig. 7

Ori decreased MPO and MDA formation but increased GSH and SOD content in LPS-induced ALI. Mice were given an intraperitoneal administration of Ori (20 and 40 mg/kg) 1 h prior to an intranasal administration of LPS. a, b, c and d MPO, MDA, GSH and SOD activity in lung tissues was determined at 12 h after LPS challenge. The values presented are the means ± SEM. (n = 5 in each group). *p < 0.05 and **p < 0.01 versus the control group, #p < 0.05 and ##p < 0.01 versus LPS group

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