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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Systematic expression analysis of ligand-receptor pairs reveals important cell-to-cell interactions inside glioma

Fig. 3

The autocrine ligand-receptor signaling network identified in glioma cells. a Ligand-receptor pairs of autocrine signals inside glioma neoplastic cells. Dots stand for ligands and receptors and arrows points from ligands to receptors. A total of 16 pairs with significant Spearman’s correlations were identified (P-value <0.05). b (c) Spearman’s correlation coefficients of two ligand-receptor pairs (DLL1-NOTCH1 and NLGN3-NRXN2) in TCGA LGG dataset. d Significantly enriched pathways for autocrine ligand-receptor pairs in tumor cells (adjusted P-value <0.05)

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Cell Communication and Signaling

ISSN: 1478-811X