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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Activin a promotes myofibroblast differentiation of endometrial mesenchymal stem cells via STAT3-dependent Smad/CTGF pathway

Fig. 1

Activin A elevated in endometriotic peritoneal fluid and ectopic endometrial MSCs expressed elevated level of ALK4. a The concentrations of Activin A in the peritoneal fluid of women with (n = 32) and without (n = 20) endometriosis were measured by ELISA. ##P < 0.01 versus the control group. b The expression of ALK4 in paired eutopic and ectopic endometrial MSCs (passage 3) derived from patients with endometriosis (n = 3) and eutopic endometrial MSCs (passage 3) derived from patients without endometriosis (n = 3) was analyzed by Western blot. The expression levels of proteins were quantified by densitometry and normalized to the expression of GAPDH. The data were presented as means ± SD. ***P < 0.001 versus eutopic endometrial MSCs from control women (C-Eutopic). ###P < 0.001 versus eutopic endometrial MSCs from petients with endometriosis (E-Eutopic)

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