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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Crystal structure of a cytocidal protein from lamprey and its mechanism of action in the selective killing of cancer cells

Fig. 4

Sialylated antennary N-glycan specificity of LIP. (a) BIAcore diagram and saturation curve of LIP bound to N003G and N025G. LIP binds to N003G and N025G with similar low affinities and rapid kinetics. Response units were plotted against protein concentrations. The KD values were calculated by BIAcore T200 analysis software (BIAevaluation version 3.0). (b) The MS/MS spectrum of the glycan from the PI-PLC-treated aqueous fraction after Triton X-114 phase separation from MCF-7 and K562 cells and human leukocytes

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