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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Amino acid response by Halofuginone in Cancer cells triggers autophagy through proteasome degradation of mTOR

Fig. 1

Halofuginone induces the amino acid starvation response (AAR) pathway. Thyroid cancer WRO cells, breast cancer MCF-7 cells, and ovarian cancer OAW-42 cells were exposed to 100 nM halofuginone (HF) for 4, 8 and 24 h. Total and phosphorylated (Ser 51) eIF2α protein levels were assessed by immunoblotting. As loading control, filters were stripped and probed with anti β-Tubulin as loading control. Representative immunoblots from three independent experiments are shown along with P-eIF2α/eIF2α band intensity ratios as index of AAR

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Cell Communication and Signaling

ISSN: 1478-811X