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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: ATG5 and ATG7 induced autophagy interplays with UPR via PERK signaling

Fig. 7

ATG5 and ATG7 influenced on autophagy, apoptosis through PERK/ATF4 signaling. a The ER stress proteins were analysed by western blotting in Ad-GFP, Ad-ATG5 + Ad-ATG7,Ad-ATG5 + Ad-ATG7 + siATF4–1,Ad-ATG5 + Ad-ATG7 + siATF4–2,Ad-ATG5 + Ad-ATG7 + siPERK1 and Ad-ATG5 + Ad-ATG7 + siPERK1+siATF4–2 induced chondrocytes. b The levels of related proteins were normalized to β-actin. (1:Ad-GFP, 2:Ad-ATG5 + Ad-ATG7, 3:Ad-ATG5 + Ad-ATG7 + siATF4–1, 4:Ad-ATG5 + Ad-ATG7+ siATF4–2, 5:Ad-ATG5 + Ad-ATG7 + siPERK1, 6:Ad-ATG5 + Ad-ATG7 + siPERK1+ siATF4–2)

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