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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Transcriptional positive cofactor 4 promotes breast cancer proliferation and metastasis through c-Myc mediated Warburg effect

Fig. 1

PC4 is upregulated in breast cancer and correlated with metastasis and poor prognosis of patients. a Immunohistochemical staining for PC4 protein in 114 cases of breast cancer (IDC and ILC) tissues, adjacent tissues and normal tissues. b The average staining score of PC4 expression in IDC and ILC derived from (a). c Immunohistochemical staining for PC4 protein in breast cancer (IDC and ILC) tissues with or without metastasis. d The average staining score of PC4 expression in IDC and ILC derived from (c). e Statistical analysis of the correlation between PC4 expression levels and overall survival in breast cancer. Data was obtained using Vant Veer breast cancer databases. f Kaplan-Meier analysis for the association of PC4 expression levels with overall survival time in breast cancer patients. Data was obtained from GSE9893. All data indicate the mean ± SD, *p < 0.05, **p < 0.01, ***p < 0.001

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Cell Communication and Signaling

ISSN: 1478-811X