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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Estrogen regulation of cardiac cAMP-L-type Ca2+ channel pathway modulates sex differences in basal contraction and responses to β2AR-mediated stress in left ventricular apical myocytes

Fig. 7

Contractile response to βAR stimulation and stress in cardiomyocytes and the influence of estrogen receptor agonists and antagonists. a Contractile responses to stress in male, sham, OVX, and OVX + E, in the presence or absence of estrogen receptor agonists and antagonists. b Corresponding Ca2+ transient amplitude in male, sham, OVX, and OVX + E in the presence or absence of estrogen receptor agonists and antagonists (n = 10 cells/7 mice). c Effect of ISO-stimulation (control) and Epi (stress) on cAMP in the presence or absence of estrogen receptor agonists and antagonists (n = 10 cells/7 mice). *P < 0.05, **P < 0.01, &&P < 0.01 vs control OVX. All data are presented as mean ± S.E.M

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Cell Communication and Signaling

ISSN: 1478-811X