Fig. 5From: Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosiscMYC-induced metabolic enzyme changes contribute to a poor prognosis in CCA patients. a and b The indicated protein levels in tumor and adjacent normal tissues from 60 CCA patients were analyzed by IHC (left) and quantified (right). Scale bars, 100 μm. c 3-year survival was evaluated for CCA patients with the indicated protein levels. Data represent the mean ± SEM, n ≥ 3. *p < 0.05, **p < 0.01. d The indicated protein levels in fresh tumor and adjacent normal tissues from 25 CCA patients were analyzed by western blot. Data represent the Mean ± SEM, n ≥ 3. *p < 0.05, **p < 0.01, NS not significantBack to article page