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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis

Fig. 5

cMYC-induced metabolic enzyme changes contribute to a poor prognosis in CCA patients. a and b The indicated protein levels in tumor and adjacent normal tissues from 60 CCA patients were analyzed by IHC (left) and quantified (right). Scale bars, 100 μm. c 3-year survival was evaluated for CCA patients with the indicated protein levels. Data represent the mean ± SEM, n ≥ 3. *p < 0.05, **p < 0.01. d The indicated protein levels in fresh tumor and adjacent normal tissues from 25 CCA patients were analyzed by western blot. Data represent the Mean ± SEM, n ≥ 3. *p < 0.05, **p < 0.01, NS not significant

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