Fig. 3

Systematic identification and clustering of glucose-dependent dynamic phosphorylation profiles. a Analysis of p-site trajectories identified four main clusters according to its phosphorylation dynamics overtime: early (short-term), early (long-lasting), intermediate and late regulated. The p-site dataset included in the analysis of trajectories was formed by the 234 p-sites matching the p-value < 0.05 and FC (Log2) > 0.3 or < − 0.3 criteria in Fig. 2d. b P-site status distribution on the four clusters identified. c Heat-map showing distribution of glucose phospho-regulated cell processes across different clusters