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Fig. 9 | Cell Communication and Signaling

Fig. 9

From: Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells

Fig. 9

Oroxylin A inhibits HSC contraction by targeting LDH-A in mice intoxicated with CCl4. Animal grouping and treatments refer to the Methods section. a Western blot analyses of MLC2 phosphorylation in liver tissues with quantification. b Immunofluorescence analyses of p-MLC2 and vimentin in liver tissues. Staining with α-SMA was used to indicate HSCs, scale bar: 20 μm. For statistical significance of this figure: **p < 0.01 vs. control; ##p < 0.01 vs. CCl4; &p < 0.05 vs. CCl4 + oroxylin A + adenovirus vector

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