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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells

Fig. 3

Oroxylin A blockade of aerobic glycolysis led to inhibition of HSC contraction. LX2 cells were treated with oroxylin A and/or 2-DG at indicated concentrations for 24 h. a Collagen gel contraction assays with quantification. b Cytoskeleton fluorescence staining, scale bar: 20 μm. c Western blot analyses of MLC2 phosphorylation with quantification. d Immunofluorescence analyses of MLC2 phosphorylation, scale bar: 20 μm. For statistical significance of this figure: *p < 0.05 vs. control, **p < 0.01 vs. control, ***p < 0.001 vs. control

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