Fig. 3
From: Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation
PAX8 suppressed thyroid carcinogenesis after LDR exposure. a Analysis of PAX8 target signature genes in BRAFV600E transformed N-thy ori-3-1 cells after fractionated (0.01Gyx10) dose of radiation. b qPCR analysis of NIS and TG expression in LDR-treated 850-5C thyroid cancer cells after PAX8 silencing. c, d Sphere and colony formation was determined in 850-5C cancer cells in same conditions as shown in B. β-actin was used as a control for normalization. *p < 0.05, **p < 0.001, and ***p < 0.0001