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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: The protein kinase Cmk2 negatively regulates the calcium/calcineurin signalling pathway and expression of calcium pump genes PMR1 and PMC1 in budding yeast

Fig. 5

Mode of Cmk2 function in the feedback regulation of calcium/calcineurin signaling pathway. In response to high levels of extracellular calcium, Ca2+ enters the cell through unknown pathways, and both calcineurin and Crz1 are activated to induce expression of target genes including CMK2, RCN1, PMR1 and PMC1 [50]. Arrows indicate activation, and T bars represent inhibition. A dashed line means that more data is needed to confirm

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