Fig. 2
From: HMGB1/autophagy pathway mediates the atrophic effect of TGF-β1 in denervated skeletal muscle
Atrophy promoting effect of TGF-β1 in gastrocnemius. a Gastrocnemius of different groups harvested 2 weeks post-denervation. b The wet weight ratio of gastrocnemius in different groups. c Morphological observation of gastrocnemius muscles in different groups by HE staining. Scale bar 50 μm. d-f Quantification of muscle fibres diameter by immunofluorescence staining of WGA. 5 mice/group, Scale bar 50 μm. *P < 0.05 vs denervation only group. #P < 0.05 vs denervation + TGF-β1 group. Den, denervation