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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation

Fig. 2

The decreased JON/A binding and P-selectin expression in Tyro3−/−, Axl−/− but not Mertk−/− platelets. Washed platelets from wild type, Tyro3−/−, Axl−/− or Mertk−/− mice were stimulated with 0.4 μg mL− 1 CRP or 0.015 U mL− 1 thrombin, followed by incubation with PE-labeled JON/A antibody (a, b) and PE-labeled anti-P-selectin antibody (c, d). The samples were analyzed using flow cytometry. MFI = mean fluorescent intensity. Mean ± SEM, NS = not significant, *** P < 0.001. One-way ANOVA and Dunnett’s multiple comparison test

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