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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: Selective deletion of hepatocyte platelet-derived growth factor receptor α and development of liver fibrosis in mice

Fig. 8

Assessment of PDGFRα expression in the human liver with hepatitis without liver fibrosis. a Immunohistochemistry of liver specimens with hepatitis showed the presence of PDGFRα at the hepatocyte membrane (arrows) and in nonparenchymal cells (arrowheads), whereas normal-liver specimens showed no PDGFRα staining. Original magnification, × 400. b Whole-cell lysates from pathologically proven hepatitis tissue without significant fibrosis (n = 7) were examined for col1α(I) and PDGFRα mRNA levels compared to those in normal liver tissue (n = 7)

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Cell Communication and Signaling

ISSN: 1478-811X