Fig. 1From: Chemotherapy-driven increases in the CDKN1A/PTN/PTPRZ1 axis promote chemoresistance by activating the NF-κB pathway in breast cancer cellsThe expression levels of PTN and PTPRZ1 were increased in breast cancer tissue after chemotherapy. PTN (a) and PTPRZ1 (b) expression data in human normal breast tissue (n = 291) and breast cancer tissue (n = 1085) from breast cancer patients without chemotherapy were obtained from the GEPIA database (http://gepia.cancer-pku.cn/index.html), Student’s t-test, *p < 0.05. c The correlation analyses of PTN and PTPRZ1 expression in breast cancer specimens without chemotherapy from the GEPIA database are shown, n = 1085, p = 0.7557, Pearson’s r test. Paired expression data of PTN (d) and PTPRZ1 (e) in human breast cancer specimens before and after adjuvant chemotherapy were obtained from the GEO database (https://www.ncbi.nlm.nih.gov/geo/), n = 69, t-test, *p < 0.05, **p < 0.01. f The correlation analyses of PTN and PTPRZ1 expression in breast cancer specimens after adjuvant chemotherapy is shown, n = 69, p < 0.001, Pearson’s r testBack to article page